12/2/2023 0 Comments Western blot hiv principle![]() ![]() Tests selected to screen donor blood and tissue must provide a high degree of confidence that HIV is not present (that is, a high sensitivity). Principles Screening donor blood and cellular products Autoimmune diseases, such as systemic lupus erythematosus, can also cause false positive results. Nonspecific reactions, hypergammaglobulinemia, or the presence of antibodies directed to other infectious agents that may be antigenically similar to HIV can produce false positive results. False negative results are when the test concludes HIV is not present, when in fact the person is infected.False positive results are when the test concludes HIV is present when, in fact, the person is not infected.specificity: The percentage of the results that will be negative when HIV is not present.Īll diagnostic tests have limitations, and sometimes their use may produce erroneous or questionable results.sensitivity: The percentage of the results that will be positive when HIV is present.Performance of medical tests is often described in terms of: Antigen testing cuts the window period to approximately 16 days and NAT (Nucleic Acid Testing) further reduces this period to 12 days. The average window period with antibody tests is 22 days. The window period is the time from infection until a test can detect any change. 6 Other tests used in HIV/AIDS treatment.2.1 Screening donor blood and cellular products. ![]()
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